Quantitative proteomics identify DAB2 as a cardiac developmental regulator that inhibits WNT/[Beta]-catenin signaling

To reveal the molecular mechanisms involved in cardiac lineage determination and differentiation, we quantified the proteome of human embryonic stem cells (hESCs), cardiac progenitor cells (CPCs), and cardiomyocytes during a time course of directed differentiation by label-free quantitative proteomi...

Ausführliche Beschreibung

Bibliographische Detailangaben

Veröffentlicht in:	Proceedings of the National Academy of Sciences - PNAS 2016-01, Vol.113 (4), p.1002
Hauptverfasser:	Hofsteen, Peter, Robitaille, Aaron M, Chapman, Daniel Patrick, Moon, Randall T, Murry, Charles E
Format:	Artikel
Sprache:	eng
Schlagworte:	Binding sites Cardiomyocytes Cells Protein expression Proteomics Signal transduction
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!