Facilitated Allergen Binding (FAB) Is a Meaningful Immunological Biomarker for Monitoring Immediate Clinical Efficacy in Short-Term Peptide Allergen Immunotherapy

Facilitated Allergen Binding (FAB) Is a Meaningful Immunological Biomarker for Monitoring Immediate Clinical Efficacy in Short-Term Peptide Allergen Immunotherapy

Methods Data was collected from a DBPC dose-finding study in 198 patients who received placebo or a peptidase-hydrolysate of grass-pollen peptides at 5 visits over 4 weeks at cumulative doses of up to 370μg (EudraCT-No:2013-005445-37).

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Veröffentlicht in:Journal of allergy and clinical immunology 2016-02, Vol.137 (2), p.AB403-AB403
Hauptverfasser: Allekotte, Silke, Dr, Shamji, Mohamed H., Dr, Zadoyan, Gregor V., Dr, Kasche, Elena M., Ms, Shah-Hosseini, Kija, Dr, Astvatsatourov, Anatoli, Dr, Pirotton, Sabine, Dr, Caplanusi, Adrian, Dr, Durham, Stephen R., Prof, Mosges, Ralph, Prof
Format: Artikel
Sprache:eng
Schlagworte:
Allergies
Allergy and Immunology
Immunology
Immunotherapy
Peptides
Short term
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Zusammenfassung:Methods Data was collected from a DBPC dose-finding study in 198 patients who received placebo or a peptidase-hydrolysate of grass-pollen peptides at 5 visits over 4 weeks at cumulative doses of up to 370μg (EudraCT-No:2013-005445-37).
ISSN:0091-6749
1097-6825
DOI:10.1016/j.jaci.2015.12.1249