Structure, chaperone activity, and aggregation of wild-type and R12C mutant [alpha]B-crystallins in the presence of thermal stress and calcium ion - Implications for role of calcium in cataract pathogenesis

The current study was performed with the aim to evaluate the chaperoning ability, structural features, and aggregation propensity of wild-type and R12C mutant [alpha]B-crystallins ([alpha]B-Cry) under thermal stress and in the presence of calcium ion. The results of different spectroscopic analyses...

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Veröffentlicht in:	Biochemistry (Moscow) 2016-02, Vol.81 (2), p.122
Hauptverfasser:	Ragerdi Kashani, M, Yousefi, R, Akbarian, M, Alavianmehr, M M, Ghasemi, Y
Format:	Artikel
Sprache:	eng
Schlagworte:	Biochemistry Calcium Cataracts Heat shock proteins Mutants Pathogenesis Solvents Thermal stress
Online-Zugang:	Volltext
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