Regulation of Rac1 and Reactive Oxygen Species Production in Response to Infection of Gastrointestinal Epithelia: e1005382

Generation of reactive oxygen species (ROS) during infection is an immediate host defense leading to microbial killing. APE1 is a multifunctional protein induced by ROS and after induction, protects against ROS-mediated DNA damage. Rac1 and NAPDH oxidase (Nox1) are important contributors of ROS gene...

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Veröffentlicht in:	PLoS pathogens 2016-01, Vol.12 (2)
Hauptverfasser:	Hartog, Gerco den, Chattopadhyay, Ranajoy, Ablack, Amber, Hall, Emily H, Butcher, Lindsay D, Bhattacharyya, Asima, Eckmann, Lars, Harris, Paul R, Das, Soumita, Ernst, Peter B, Crowe, Sheila E
Format:	Artikel
Sprache:	eng
Schlagworte:	Bacterial infections Cancer Deoxyribonucleic acid DNA DNA damage Experiments Funding Infections Microscopy Oxidative stress Oxygen Pathogens Physiology Proteins Ulcers
Online-Zugang:	Volltext
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