Febuxostat protects rats against lipopolysaccharide-induced lung inflammation in a dose-dependent manner

The aim of the present work was to investigate possible protective effects of febuxostat, a highly potent xanthine oxidase inhibitor, against acute lung injury (ALI) induced by lipopolysaccharide (LPS) in rats. Male Sprague Dawley rats were randomly divided into six groups, as follows: (i) vehicle c...

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Veröffentlicht in:Naunyn-Schmiedeberg's archives of pharmacology 2016-03, Vol.389 (3), p.269-278
Hauptverfasser: Fahmi, Alaa N. A., Shehatou, George S. G., Shebl, Abdelhadi M., Salem, Hatem A.
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Sprache:eng
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