Plasma and intracellular exposure to ganciclovir in adult renal transplant recipients: is there an association with haematological toxicity?

Ganciclovir is the most widely used treatment for cytomegalovirus infections. However, neutropenia is a frequent associated adverse effect leading to a decrease in the ganciclovir dose or discontinuation of the therapy, thereby favouring viral resistance. In the present study, the objectives were: (...

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Veröffentlicht in:Journal of antimicrobial chemotherapy 2016-02, Vol.71 (2), p.484-489
Hauptverfasser: Billat, Pierre-André, Woillard, Jean-Baptiste, Essig, Marie, Sauvage, François-Ludovic, Picard, Nicolas, Alain, Sophie, Neely, Michael, Marquet, Pierre, Saint-Marcoux, Franck
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Sprache:eng
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