Handling low haemoglobin and iron deficiency in a blood donor population
Background Blood donors with low haemoglobin concentration (Hb) and iron deficiency are well‐known challenges in any blood bank setting. The handling of such donors is complex, and although iron deficiency is a frequent cause of anaemia, there are differential diagnoses. Aims The primary aims were t...
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| Veröffentlicht in: | ISBT science series 2016-01, Vol.11 (S1), p.235-242 |
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| creator | Magnussen, K. Ladelund, S. |
| description | Background
Blood donors with low haemoglobin concentration (Hb) and iron deficiency are well‐known challenges in any blood bank setting. The handling of such donors is complex, and although iron deficiency is a frequent cause of anaemia, there are differential diagnoses.
Aims
The primary aims were to standardize and optimize the handling of blood donors with Hb below the limit for donation. Secondary aims were to deal with all issues related to high or low either Hb or ferritin in blood donors.
Methods
The problem was approached by centralizing measurement of Hb, initiating ferritin measurements and establishing Centre for Donor Haemoglobin and Iron. An algorithm was created, taking Hb and ferritin into account. The donors were mainly contacted by post, but when Hb was low or when there was insufficient effect of previously given iron supplementation, the donors were contacted by phone to improve compliance. Hb was measured on Sysmex‐XE2100D at every donation. Ferritin was measured once in all donors, at every 10th donation and repeated when outside 60–300 μg/l or Hb low at the previous donation.
Results
February 1st 2012–February 1st 2015, 71 450 donors (53·5%women/46·5%men) donated 281 814 units of whole blood. Due to changes in calibration, Hb changes could only be monitored over the first 24 months. Mean Hb increased in the female and male donors (P |
| doi_str_mv | 10.1111/voxs.12183 |
| format | Article |
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Blood donors with low haemoglobin concentration (Hb) and iron deficiency are well‐known challenges in any blood bank setting. The handling of such donors is complex, and although iron deficiency is a frequent cause of anaemia, there are differential diagnoses.
Aims
The primary aims were to standardize and optimize the handling of blood donors with Hb below the limit for donation. Secondary aims were to deal with all issues related to high or low either Hb or ferritin in blood donors.
Methods
The problem was approached by centralizing measurement of Hb, initiating ferritin measurements and establishing Centre for Donor Haemoglobin and Iron. An algorithm was created, taking Hb and ferritin into account. The donors were mainly contacted by post, but when Hb was low or when there was insufficient effect of previously given iron supplementation, the donors were contacted by phone to improve compliance. Hb was measured on Sysmex‐XE2100D at every donation. Ferritin was measured once in all donors, at every 10th donation and repeated when outside 60–300 μg/l or Hb low at the previous donation.
Results
February 1st 2012–February 1st 2015, 71 450 donors (53·5%women/46·5%men) donated 281 814 units of whole blood. Due to changes in calibration, Hb changes could only be monitored over the first 24 months. Mean Hb increased in the female and male donors (P < 0·0001). Percentage of donors with low Hb decreased (women OR/month = 0·98; P < 0·0001; men OR/month = 0·97; P < 0·0001).
Summary/conclusions
The program of iron supplementation restricted only to those that would benefit has led to an increase in Hb and a reduction in the number of donors with low Hb.</description><identifier>ISSN: 1751-2816</identifier><identifier>EISSN: 1751-2824</identifier><identifier>DOI: 10.1111/voxs.12183</identifier><language>eng</language><publisher>Oxford: Blackwell Publishing Ltd</publisher><subject>anaemia ; blood donors ; ferritin ; haemoglobin ; iron deficiency ; iron supplementation</subject><ispartof>ISBT science series, 2016-01, Vol.11 (S1), p.235-242</ispartof><rights>2016 International Society of Blood Transfusion</rights><rights>Copyright ISBT Science Series © 2016 International Society of Blood Transfusion</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c1843-a6a7afc96b0afd9760ea8816faf4d346fd2d9bc93410d0afb15e41c3d6e26f903</citedby><cites>FETCH-LOGICAL-c1843-a6a7afc96b0afd9760ea8816faf4d346fd2d9bc93410d0afb15e41c3d6e26f903</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://onlinelibrary.wiley.com/doi/pdf/10.1111%2Fvoxs.12183$$EPDF$$P50$$Gwiley$$H</linktopdf><linktohtml>$$Uhttps://onlinelibrary.wiley.com/doi/full/10.1111%2Fvoxs.12183$$EHTML$$P50$$Gwiley$$H</linktohtml><link.rule.ids>314,777,781,1412,27905,27906,45555,45556</link.rule.ids></links><search><creatorcontrib>Magnussen, K.</creatorcontrib><creatorcontrib>Ladelund, S.</creatorcontrib><title>Handling low haemoglobin and iron deficiency in a blood donor population</title><title>ISBT science series</title><addtitle>VOXS</addtitle><description>Background
Blood donors with low haemoglobin concentration (Hb) and iron deficiency are well‐known challenges in any blood bank setting. The handling of such donors is complex, and although iron deficiency is a frequent cause of anaemia, there are differential diagnoses.
Aims
The primary aims were to standardize and optimize the handling of blood donors with Hb below the limit for donation. Secondary aims were to deal with all issues related to high or low either Hb or ferritin in blood donors.
Methods
The problem was approached by centralizing measurement of Hb, initiating ferritin measurements and establishing Centre for Donor Haemoglobin and Iron. An algorithm was created, taking Hb and ferritin into account. The donors were mainly contacted by post, but when Hb was low or when there was insufficient effect of previously given iron supplementation, the donors were contacted by phone to improve compliance. Hb was measured on Sysmex‐XE2100D at every donation. Ferritin was measured once in all donors, at every 10th donation and repeated when outside 60–300 μg/l or Hb low at the previous donation.
Results
February 1st 2012–February 1st 2015, 71 450 donors (53·5%women/46·5%men) donated 281 814 units of whole blood. Due to changes in calibration, Hb changes could only be monitored over the first 24 months. Mean Hb increased in the female and male donors (P < 0·0001). Percentage of donors with low Hb decreased (women OR/month = 0·98; P < 0·0001; men OR/month = 0·97; P < 0·0001).
Summary/conclusions
The program of iron supplementation restricted only to those that would benefit has led to an increase in Hb and a reduction in the number of donors with low Hb.</description><subject>anaemia</subject><subject>blood donors</subject><subject>ferritin</subject><subject>haemoglobin</subject><subject>iron deficiency</subject><subject>iron supplementation</subject><issn>1751-2816</issn><issn>1751-2824</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2016</creationdate><recordtype>article</recordtype><recordid>eNp9kEFPAjEQhRujiYhe_AVNvJkstttud_eoqGAkclCRW9Pdtlhc2rUFgX_v4ipH5zKTl-_NTB4A5xj1cFNXX24TejjGGTkAHZwmOIqzmB7uZ8yOwUkIc4QSmqW0A4ZDYWVl7AxWbg3fhVq4WeUKY2GjQ-OdhVJpUxplyy3cybConJNQOus8rF29qsTSOHsKjrSogjr77V3wen_30h9Go_HgoX89ikqcURIJJlKhy5wVSGiZpwwpkTVvaaGpJJRpGcu8KHNCMZINUuBEUVwSyVTMdI5IF1y0e2vvPlcqLPncrbxtTnKcMowpQYw11GVLld6F4JXmtTcL4bccI75Liu-S4j9JNTBu4bWp1PYfkk_G0-c_T9R6TFiqzd4j_AdnKUkT_vY04NMsub3JJzl_JN-xSXtB</recordid><startdate>201601</startdate><enddate>201601</enddate><creator>Magnussen, K.</creator><creator>Ladelund, S.</creator><general>Blackwell Publishing Ltd</general><general>Wiley Subscription Services, Inc</general><scope>BSCLL</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>K9.</scope></search><sort><creationdate>201601</creationdate><title>Handling low haemoglobin and iron deficiency in a blood donor population</title><author>Magnussen, K. ; Ladelund, S.</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c1843-a6a7afc96b0afd9760ea8816faf4d346fd2d9bc93410d0afb15e41c3d6e26f903</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2016</creationdate><topic>anaemia</topic><topic>blood donors</topic><topic>ferritin</topic><topic>haemoglobin</topic><topic>iron deficiency</topic><topic>iron supplementation</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Magnussen, K.</creatorcontrib><creatorcontrib>Ladelund, S.</creatorcontrib><collection>Istex</collection><collection>CrossRef</collection><collection>ProQuest Health & Medical Complete (Alumni)</collection><jtitle>ISBT science series</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Magnussen, K.</au><au>Ladelund, S.</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Handling low haemoglobin and iron deficiency in a blood donor population</atitle><jtitle>ISBT science series</jtitle><addtitle>VOXS</addtitle><date>2016-01</date><risdate>2016</risdate><volume>11</volume><issue>S1</issue><spage>235</spage><epage>242</epage><pages>235-242</pages><issn>1751-2816</issn><eissn>1751-2824</eissn><abstract>Background
Blood donors with low haemoglobin concentration (Hb) and iron deficiency are well‐known challenges in any blood bank setting. The handling of such donors is complex, and although iron deficiency is a frequent cause of anaemia, there are differential diagnoses.
Aims
The primary aims were to standardize and optimize the handling of blood donors with Hb below the limit for donation. Secondary aims were to deal with all issues related to high or low either Hb or ferritin in blood donors.
Methods
The problem was approached by centralizing measurement of Hb, initiating ferritin measurements and establishing Centre for Donor Haemoglobin and Iron. An algorithm was created, taking Hb and ferritin into account. The donors were mainly contacted by post, but when Hb was low or when there was insufficient effect of previously given iron supplementation, the donors were contacted by phone to improve compliance. Hb was measured on Sysmex‐XE2100D at every donation. Ferritin was measured once in all donors, at every 10th donation and repeated when outside 60–300 μg/l or Hb low at the previous donation.
Results
February 1st 2012–February 1st 2015, 71 450 donors (53·5%women/46·5%men) donated 281 814 units of whole blood. Due to changes in calibration, Hb changes could only be monitored over the first 24 months. Mean Hb increased in the female and male donors (P < 0·0001). Percentage of donors with low Hb decreased (women OR/month = 0·98; P < 0·0001; men OR/month = 0·97; P < 0·0001).
Summary/conclusions
The program of iron supplementation restricted only to those that would benefit has led to an increase in Hb and a reduction in the number of donors with low Hb.</abstract><cop>Oxford</cop><pub>Blackwell Publishing Ltd</pub><doi>10.1111/voxs.12183</doi><tpages>8</tpages></addata></record> |
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| identifier | ISSN: 1751-2816 |
| ispartof | ISBT science series, 2016-01, Vol.11 (S1), p.235-242 |
| issn | 1751-2816 1751-2824 |
| language | eng |
| recordid | cdi_proquest_journals_1761143066 |
| source | Wiley Online Library Journals Frontfile Complete |
| subjects | anaemia blood donors ferritin haemoglobin iron deficiency iron supplementation |
| title | Handling low haemoglobin and iron deficiency in a blood donor population |
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