A novel acetylcholinesterase inhibitor and calcium channel blocker SCR-1693 improves A[beta]^sub 25-35^-impaired mouse cognitive function

Rationale The mechanism involved in AD is complex, which has prompted to develop compounds that could simultaneously interact with several potential targets. Here, we report a new synthesized compound SCR-1693 which is designed to target both AChE and calcium channels that are potential for AD thera...

Ausführliche Beschreibung

Bibliographische Detailangaben

Veröffentlicht in:	Psychopharmacology 2016-02, Vol.233 (4), p.599
Hauptverfasser:	Zhang, Zhengping, Chen, Rong, An, Wenji, Wang, Chunmei, Liao, Gaoyong, Dong, Xiaoliang, Bi, Aijing, Yin, Zhimin, Luo, Lan
Format:	Artikel
Sprache:	eng
Schlagworte:	Calcium Cognition & reasoning Drug therapy Learning Memory Rodents
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!