Age-associated changes in long-chain fatty acid profile during healthy aging promote pro-inflammatory monocyte polarization via PPAR[gamma]

Summary Differences in lipid metabolism associate with age-related disease development and lifespan. Inflammation is a common link between metabolic dysregulation and aging. Saturated fatty acids (FAs) initiate pro-inflammatory signalling from many cells including monocytes; however, no existing stu...

Ausführliche Beschreibung

Bibliographische Detailangaben

Veröffentlicht in:	Aging cell 2016-02, Vol.15 (1), p.128
Hauptverfasser:	Pararasa, Chathyan, Ikwuobe, John, Shigdar, Shahjahan, Boukouvalas, Alexis, Nabney, Ian T, Brown, James E, Devitt, Andrew, Bailey, Clifford J, Bennett, Stuart J, Griffiths, Helen R
Format:	Artikel
Sprache:	eng
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!