Heterocyclic Ketene Aminals: Scaffolds for Heterocycle Molecular Diversity
Heterocyclic ketene aminals (HKAs) have proven to be a class of fascinating and versatile synthetic building blocks for use in the construction of heterocyclic or fused heterocyclic compounds. The bicyclic, tricyclic, and tetracyclic nitrogen‐containing analogues with HKA skeleton widely exist in na...
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Veröffentlicht in: | European journal of organic chemistry 2014-02, Vol.2014 (6), p.1129-1145 |
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creator | Wang, Kai-Min Yan, Sheng-Jiao Lin, Jun |
description | Heterocyclic ketene aminals (HKAs) have proven to be a class of fascinating and versatile synthetic building blocks for use in the construction of heterocyclic or fused heterocyclic compounds. The bicyclic, tricyclic, and tetracyclic nitrogen‐containing analogues with HKA skeleton widely exist in natural and synthetic drugs. To understand and to master the reaction properties of HKAs and to construct other new fused heterocycles in the future, it is very important and necessary to investigate HKAs. This review covers the relevant contributions of the last twenty years with respect to the developments and applications of HKAs, categorized by reaction type.
Heterocyclic ketene aminals (HKAs) have proven to be fascinating and versatile synthetic building blocks for use in the construction of heterocyclic or fused heterocyclic compounds. This review covers the more relevant contributions of the last twenty years with respect to the developments and applications of HKAs according to reaction type. |
doi_str_mv | 10.1002/ejoc.201300929 |
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Heterocyclic ketene aminals (HKAs) have proven to be fascinating and versatile synthetic building blocks for use in the construction of heterocyclic or fused heterocyclic compounds. This review covers the more relevant contributions of the last twenty years with respect to the developments and applications of HKAs according to reaction type.</description><identifier>ISSN: 1434-193X</identifier><identifier>EISSN: 1099-0690</identifier><identifier>DOI: 10.1002/ejoc.201300929</identifier><language>eng</language><publisher>Weinheim: WILEY-VCH Verlag</publisher><subject>Cumulenes ; Ketene aminals ; Michael addition ; Multicomponent reactions ; Nitrogen heterocycles</subject><ispartof>European journal of organic chemistry, 2014-02, Vol.2014 (6), p.1129-1145</ispartof><rights>Copyright © 2014 WILEY‐VCH Verlag GmbH & Co. KGaA, Weinheim</rights><rights>Copyright © 2014 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c3559-fff24e11058388caeae19d5e395d6b00024b91774fa69710e79ad2871450b8aa3</citedby><cites>FETCH-LOGICAL-c3559-fff24e11058388caeae19d5e395d6b00024b91774fa69710e79ad2871450b8aa3</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://onlinelibrary.wiley.com/doi/pdf/10.1002%2Fejoc.201300929$$EPDF$$P50$$Gwiley$$H</linktopdf><linktohtml>$$Uhttps://onlinelibrary.wiley.com/doi/full/10.1002%2Fejoc.201300929$$EHTML$$P50$$Gwiley$$H</linktohtml><link.rule.ids>314,780,784,1417,27924,27925,45574,45575</link.rule.ids></links><search><creatorcontrib>Wang, Kai-Min</creatorcontrib><creatorcontrib>Yan, Sheng-Jiao</creatorcontrib><creatorcontrib>Lin, Jun</creatorcontrib><title>Heterocyclic Ketene Aminals: Scaffolds for Heterocycle Molecular Diversity</title><title>European journal of organic chemistry</title><addtitle>Eur. J. Org. Chem</addtitle><description>Heterocyclic ketene aminals (HKAs) have proven to be a class of fascinating and versatile synthetic building blocks for use in the construction of heterocyclic or fused heterocyclic compounds. The bicyclic, tricyclic, and tetracyclic nitrogen‐containing analogues with HKA skeleton widely exist in natural and synthetic drugs. To understand and to master the reaction properties of HKAs and to construct other new fused heterocycles in the future, it is very important and necessary to investigate HKAs. This review covers the relevant contributions of the last twenty years with respect to the developments and applications of HKAs, categorized by reaction type.
Heterocyclic ketene aminals (HKAs) have proven to be fascinating and versatile synthetic building blocks for use in the construction of heterocyclic or fused heterocyclic compounds. This review covers the more relevant contributions of the last twenty years with respect to the developments and applications of HKAs according to reaction type.</description><subject>Cumulenes</subject><subject>Ketene aminals</subject><subject>Michael addition</subject><subject>Multicomponent reactions</subject><subject>Nitrogen heterocycles</subject><issn>1434-193X</issn><issn>1099-0690</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2014</creationdate><recordtype>article</recordtype><recordid>eNqFkMFPwjAUhxujiYhePS_xPGzXdl29EUQQUA5oNF6a0r0mw0GxHer-e0dm1Jun917yfS-__BA6J7hHME4uYeVML8GEYiwTeYA6BEsZ41Tiw2ZnlMVE0udjdBLCCjdMmpIOmoyhAu9MbcrCRNPm2EDUXxcbXYaraGG0ta7MQ2Sdj35RiO5cCWZXah9dF-_gQ1HVp-jINhacfc8uerwZPgzG8Ww-uh30Z7GhnMvYWpswIATzjGaZ0aCByJwDlTxPl02whC0lEYJZnUpBMAip8yQThHG8zLSmXXTR_t1697aDUKmV2_l9YEUE5xmjKaMN1Wsp410IHqza-mKtfa0IVvu-1L4v9dNXI8hW-ChKqP-h1XAyH_x149YtQgWfP672ryoVVHD1dD9Sg9FLtuBkrKb0C4YKfZM</recordid><startdate>201402</startdate><enddate>201402</enddate><creator>Wang, Kai-Min</creator><creator>Yan, Sheng-Jiao</creator><creator>Lin, Jun</creator><general>WILEY-VCH Verlag</general><general>WILEY‐VCH Verlag</general><general>Wiley Subscription Services, Inc</general><scope>BSCLL</scope><scope>AAYXX</scope><scope>CITATION</scope></search><sort><creationdate>201402</creationdate><title>Heterocyclic Ketene Aminals: Scaffolds for Heterocycle Molecular Diversity</title><author>Wang, Kai-Min ; Yan, Sheng-Jiao ; Lin, Jun</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c3559-fff24e11058388caeae19d5e395d6b00024b91774fa69710e79ad2871450b8aa3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2014</creationdate><topic>Cumulenes</topic><topic>Ketene aminals</topic><topic>Michael addition</topic><topic>Multicomponent reactions</topic><topic>Nitrogen heterocycles</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Wang, Kai-Min</creatorcontrib><creatorcontrib>Yan, Sheng-Jiao</creatorcontrib><creatorcontrib>Lin, Jun</creatorcontrib><collection>Istex</collection><collection>CrossRef</collection><jtitle>European journal of organic chemistry</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Wang, Kai-Min</au><au>Yan, Sheng-Jiao</au><au>Lin, Jun</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Heterocyclic Ketene Aminals: Scaffolds for Heterocycle Molecular Diversity</atitle><jtitle>European journal of organic chemistry</jtitle><addtitle>Eur. J. Org. Chem</addtitle><date>2014-02</date><risdate>2014</risdate><volume>2014</volume><issue>6</issue><spage>1129</spage><epage>1145</epage><pages>1129-1145</pages><issn>1434-193X</issn><eissn>1099-0690</eissn><abstract>Heterocyclic ketene aminals (HKAs) have proven to be a class of fascinating and versatile synthetic building blocks for use in the construction of heterocyclic or fused heterocyclic compounds. The bicyclic, tricyclic, and tetracyclic nitrogen‐containing analogues with HKA skeleton widely exist in natural and synthetic drugs. To understand and to master the reaction properties of HKAs and to construct other new fused heterocycles in the future, it is very important and necessary to investigate HKAs. This review covers the relevant contributions of the last twenty years with respect to the developments and applications of HKAs, categorized by reaction type.
Heterocyclic ketene aminals (HKAs) have proven to be fascinating and versatile synthetic building blocks for use in the construction of heterocyclic or fused heterocyclic compounds. This review covers the more relevant contributions of the last twenty years with respect to the developments and applications of HKAs according to reaction type.</abstract><cop>Weinheim</cop><pub>WILEY-VCH Verlag</pub><doi>10.1002/ejoc.201300929</doi><tpages>17</tpages></addata></record> |
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subjects | Cumulenes Ketene aminals Michael addition Multicomponent reactions Nitrogen heterocycles |
title | Heterocyclic Ketene Aminals: Scaffolds for Heterocycle Molecular Diversity |
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