Synthetic Routes towards Fluorine-Containing Amino Sugars: Synthesis of Fluorinated Analogues of Tomosamine and 4-Amino-4-deoxyarabinose

Fluorinated analogues of bioactive amino sugars are of high interest in medicinal chemistry. We developed a straightforward synthetic route towards this class of carbohydrates by applying a titanium‐mediated aldol addition. Thus, two‐carbon chain elongations of serine‐ and threonine‐derived aldehyde...

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Veröffentlicht in:	European journal of organic chemistry 2014-04, Vol.2014 (12), p.2451-2459
Hauptverfasser:	Albler, Christopher, Schmid, Walther
Format:	Artikel
Sprache:	eng
Schlagworte:	Aldol reactions Carbohydrates Chiral auxilia­ries Fluorine
Online-Zugang:	Volltext
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