Chronic Mesenteric Ischemia: A Rare Cause of Chronic Abdominal Pain

Abstract Background Chronic mesenteric ischemia is a rare disease with nonspecific clinical symptoms, such as chronic postprandial abdominal pain and weight loss. Diagnostic modalities and revascularization techniques have evolved during the past 20 years. The significance of stenosis in a single sp...

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Veröffentlicht in:The American journal of medicine 2015-12, Vol.128 (12), p.1363.e1-1363.e8
Hauptverfasser: Barret, Maximilien, MD, MSc, Martineau, Chloé, MD, Rahmi, Gabriel, MD, MSc, Pellerin, Olivier, MD, MSc, Sapoval, Marc, MD, PhD, Alsac, Jean-Marc, MD, PhD, Fabiani, Jean-Noël, MD, PhD, Malamut, Georgia, MD, PhD, Samaha, Elia, MD, Cellier, Christophe, MD, PhD
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Sprache:eng
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Zusammenfassung:Abstract Background Chronic mesenteric ischemia is a rare disease with nonspecific clinical symptoms, such as chronic postprandial abdominal pain and weight loss. Diagnostic modalities and revascularization techniques have evolved during the past 20 years. The significance of stenosis in a single splanchnic vessel remains unclear. Our aims were to assess the outcomes of 2 revascularization techniques and report on the diagnostic modalities of splanchnic vessel stenoses. Methods The demographic data, medical history, technical characteristics, and outcomes of the revascularization procedures were recorded for all of the patients admitted for endovascular revascularization or open surgical revascularization of the splanchnic vessels as treatment for chronic mesenteric ischemia in our tertiary referral center since 2000. Results Fifty-four patients were included in this study: 43 received endovascular revascularization, and 11 had open surgical revascularization. The symptoms were abdominal pain, weight loss, and diarrhea in 98%, 53%, and 25% of the cases, respectively. Computed tomography angiography was the key diagnostic tool for 60% of the patients. A single-vessel stenosis was found in one-third of the patients. Endovascular and open revascularization had similar early and late outcomes, and no 30-day mortality was observed. However, we did observe higher morbidity in the open revascularization group (73% vs 19%, P
ISSN:0002-9343
1555-7162
DOI:10.1016/j.amjmed.2015.07.029