Metabolic engineering of Escherichia coli for 1,3-butanediol biosynthesis through the inverted fatty acid [beta]-oxidation cycle

The feasibility of 1,3-butanediol biosynthesis through the inverted cycle of fatty acid [beta]-oxidation in Escherichia coli cells was investigated by the rational metabolic engineering approach. CoA-dependent aldehyde dehydrogenase MhpF and alcohol dehydrogenases FucO and YqhD were used as terminal...

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Veröffentlicht in:	Applied biochemistry and microbiology 2016-01, Vol.52 (1), p.15
Hauptverfasser:	Gulevich, A Yu, Skorokhodova, A Yu, Stasenko, A A, Shakulov, R S, Debabov, V G
Format:	Artikel
Sprache:	eng
Schlagworte:	Biosynthesis Cell cycle Dehydrogenase E coli Ethanol Fatty acids Feasibility studies Fermentation Inactivation Metabolic disorders Oxidation
Online-Zugang:	Volltext
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