An RNA motif advances transcription by preventing Rho-dependent termination

The transcription termination factor Rho associates with most nascent bacterial RNAs as they emerge from RNA polymerase. However, pharmacological inhibition of Rho derepresses only a small fraction of these transcripts. What, then, determines the specificity of Rho-dependent transcription terminatio...

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Veröffentlicht in:	Proceedings of the National Academy of Sciences - PNAS 2015-12, Vol.112 (50), p.E6835-E6843
Hauptverfasser:	Sevostyanova, Anastasia, Groisman, Eduardo A.
Format:	Artikel
Sprache:	eng
Schlagworte:	Amino Acid Sequence Base Sequence Binding sites Biological Sciences Genes, Bacterial Molecular Sequence Data Nucleic Acid Conformation PNAS Plus Rho Factor - physiology Ribonucleic acid RNA RNA polymerase RNA, Bacterial - chemistry RNA, Bacterial - physiology Salmonella Salmonella - genetics Terminator Regions, Genetic Transcription factors Transcription, Genetic - physiology
Online-Zugang:	Volltext
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