Assessment of the sensitizing potency of preservatives with chance of skin contact by the loose-fit coculture-based sensitization assay (LCSA)

Parabens, methylisothiazolinone (MI) and its derivative methylchloroisothiazolinone (MCI), are commonly used as preservatives in personal care products. They can cause hypersensitivity reactions of the human skin. We have tested a set of nine parabens, MI alone and in combination with MCI in the loo...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	Archives of toxicology 2015-12, Vol.89 (12), p.2339-2344
Hauptverfasser:	Sonnenburg, Anna, Schreiner, Maximilian, Stahlmann, Ralf
Format:	Artikel
Sprache:	eng
Schlagworte:	Allergies Biomedical and Life Sciences Biomedicine Coculture Techniques Cytotoxicity Dendritic Cells - drug effects Dendritic Cells - pathology Dermatitis, Allergic Contact - etiology Environmental Health Flow Cytometry Humans Immunotoxicology Keratinocytes - drug effects Keratinocytes - pathology Occupational Medicine/Industrial Medicine Parabens - administration & dosage Parabens - toxicity Pharmacology/Toxicology Preservatives Preservatives, Pharmaceutical - administration & dosage Preservatives, Pharmaceutical - toxicity Skin Skin - drug effects Skin - pathology Skin Irritancy Tests Thiazoles - administration & dosage Thiazoles - toxicity
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!