Evaluation of Laxative Activity of Vaishvanara Churna: An Ayurvedic Formulation
Vaishvanara churna is an Ayurvedic formulation traditionally used as laxative, analgesic, anti-inflammatory and arthritic agent. Since there was no scientific proof of this formulation as laxative, we aimed to screen the laxative activity of Vaishvanara churna in rats. Rats were divided into 4 group...
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| Veröffentlicht in: | Advances in Bioscience and Clinical Medicine 2014-07, Vol.2 (2), p.64 |
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| creator | Bagepalli Srinivas Ashok Kumar Saran, Gopisetty Harshada, Ramachandra Kupphalli Narayanswamy Bharath Kumar, Arun Kulasekar, Kruba Sreeramulu |
| description | Vaishvanara churna is an Ayurvedic formulation traditionally used as laxative, analgesic, anti-inflammatory and arthritic agent. Since there was no scientific proof of this formulation as laxative, we aimed to screen the laxative activity of Vaishvanara churna in rats. Rats were divided into 4 groups, 6 animals each. First group acted as control, second group as standard (Senna, 30 mg/kg) and third and fourth groups received aqueous extract of Vaishvanara churna at doses 100 and 200 mg/kg, respectively. Compared with the control group, aqueous extract of Vaishvanara churna at 100 mg/kg did not lead to a statistically significant increase in 8th-h fecal output; however, 16th-h output was significantly increased (p |
| doi_str_mv | 10.7575/aiac.abcmed.14.02.02.11 |
| format | Article |
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Since there was no scientific proof of this formulation as laxative, we aimed to screen the laxative activity of Vaishvanara churna in rats. Rats were divided into 4 groups, 6 animals each. First group acted as control, second group as standard (Senna, 30 mg/kg) and third and fourth groups received aqueous extract of Vaishvanara churna at doses 100 and 200 mg/kg, respectively. Compared with the control group, aqueous extract of Vaishvanara churna at 100 mg/kg did not lead to a statistically significant increase in 8th-h fecal output; however, 16th-h output was significantly increased (p<0.01). Vaishvanara churna at 200 mg/kg significantly increased the fecal output of rats (p<0.01) compared with that of the control group both at 8th and 16th hours. 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Since there was no scientific proof of this formulation as laxative, we aimed to screen the laxative activity of Vaishvanara churna in rats. Rats were divided into 4 groups, 6 animals each. First group acted as control, second group as standard (Senna, 30 mg/kg) and third and fourth groups received aqueous extract of Vaishvanara churna at doses 100 and 200 mg/kg, respectively. Compared with the control group, aqueous extract of Vaishvanara churna at 100 mg/kg did not lead to a statistically significant increase in 8th-h fecal output; however, 16th-h output was significantly increased (p<0.01). Vaishvanara churna at 200 mg/kg significantly increased the fecal output of rats (p<0.01) compared with that of the control group both at 8th and 16th hours. Our investigation showed that Vaishvanara churna may possess potent laxative activity.</abstract><cop>Footscray</cop><pub>Australian International Academic Centre PTY. 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| title | Evaluation of Laxative Activity of Vaishvanara Churna: An Ayurvedic Formulation |
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