5'-AMP activated protein kinase [alpha]2 controls substrate metabolism during post-exercise recovery via regulation of pyruvate dehydrogenase kinase 4

Key points There is lower fat oxidation during post-exercise recovery in mice lacking 5'-AMP activated protein kinase [alpha]2 (AMPK[alpha]2). AMPK[alpha]2 is involved in post-transcriptional and not transcriptional regulation of pyruvate dehydrogenase kinase 4 (PDK4) in muscle. Exercise-induce...

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Veröffentlicht in:The Journal of physiology 2015-11, Vol.593 (21), p.4765
Hauptverfasser: Fritzen, Andreas Mæchel, Lundsgaard, Anne-Marie, Jeppesen, Jacob, Christiansen, Mette Landau Brabæk, Bienso, Rasmus, Dyck, Jason R B, Pilegaard, Henriette, Kiens, Bente
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Sprache:eng
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