Dialogue between E. coli free radical pathways and the mitochondria of C. elegans

The microbial world presents a complex palette of opportunities and dangers to animals, which have developed surveillance and response strategies to hints of microbial intent. We show here that the mitochondrial homeostatic response pathway of the nematode Caenorhabditis elegans responds to Escheric...

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Veröffentlicht in:	Proceedings of the National Academy of Sciences - PNAS 2015-10, Vol.112 (40), p.12456-12461
Hauptverfasser:	Govindan, J Amaranath, Jayamani, Elamparithi, Zhang, Xinrui, Mylonakis, Eleftherios, Ruvkun, Gary
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Animals, Genetically Modified Biological Sciences Biosynthetic Pathways - genetics Caenorhabditis elegans - genetics Caenorhabditis elegans - metabolism Caenorhabditis elegans - microbiology Caenorhabditis elegans Proteins - genetics Caenorhabditis elegans Proteins - metabolism Detoxification E coli Escherichia coli - genetics Escherichia coli - metabolism Escherichia coli - physiology Free Radicals - metabolism Gene Expression Homeostasis Host-Pathogen Interactions - genetics Microscopy, Fluorescence Mitochondria Mitochondria - metabolism Mutants Mutation Reverse Transcriptase Polymerase Chain Reaction Transcription factors Transcription Factors - genetics Transcription Factors - metabolism
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