Modeling and Prediction of Solvent Effect on Human Skin Permeability using Support Vector Regression and Random Forest

Purpose The solvent effect on skin permeability is important for assessing the effectiveness and toxicological risk of new dermatological formulations in pharmaceuticals and cosmetics development. The solvent effect occurs by diverse mechanisms, which could be elucidated by efficient and reliable pr...

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Veröffentlicht in:Pharmaceutical research 2015-11, Vol.32 (11), p.3604-3617
Hauptverfasser: Baba, Hiromi, Takahara, Jun-ichi, Yamashita, Fumiyoshi, Hashida, Mitsuru
Format: Artikel
Sprache:eng
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