Hepatitis B virus X protein promotes human hepatoma cell growth via upregulation of transcription factor AP2[alpha] and sphingosine kinase 1

Aim:Sphingosine kinase 1 (SPHK1) is involved in various cellular functions, including cell growth, migration, apoptosis, cytoskeleton architecture and calcium homoeostasis, etc. As an oncogenic kinase, SPHK1 is associated with the development and progression of cancers. The aim of this study was to...

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Veröffentlicht in:Acta pharmacologica Sinica 2015-10, Vol.36 (10), p.1228
Hauptverfasser: Lu, Zhan-ping, Xiao, Ze-lin, Yang, Zhe, Li, Jiong, Feng, Guo-xing, Chen, Fu-quan, Li, Ying-hui, Feng, Jin-yan, Gao, Yu-en, Ye, Li-hong, Zhang, Xiao-dong
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Sprache:eng
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