Extracellular RNAs: development as biomarkers of human disease
Ten ongoing studies designed to test the possibility that extracellular RNAs may serve as biomarkers in human disease are described. These studies, funded by the NIH Common Fund Extracellular RNA Communication Program, examine diverse extracellular body fluids, including plasma, serum, urine and cer...
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| Veröffentlicht in: | Journal of extracellular vesicles 2015-01, Vol.4 (1), p.27495-n/a |
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| creator | Quinn, Joseph F. Patel, Tushar Wong, David Das, Saumya Freedman, Jane E. Laurent, Louise C. Carter, Bob S. Hochberg, Fred Keuren-Jensen, Kendall Van Huentelman, Matt Spetzler, Robert S. Kalani, M. Yashar Arango, Jorge Adelson, P. David Weiner, Howard L. Gandhi, Roopali Goilav, Beatrice Putterman, Chaim Saugstad, Julie A. |
| description | Ten ongoing studies designed to test the possibility that extracellular RNAs may serve as biomarkers in human disease are described. These studies, funded by the NIH Common Fund Extracellular RNA Communication Program, examine diverse extracellular body fluids, including plasma, serum, urine and cerebrospinal fluid. The disorders studied include hepatic and gastric cancer, cardiovascular disease, chronic kidney disease, neurodegenerative disease, brain tumours, intracranial haemorrhage, multiple sclerosis and placental disorders. Progress to date and the plans for future studies are outlined. |
| doi_str_mv | 10.3402/jev.v4.27495 |
| format | Article |
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Kalani, M. Yashar ; Arango, Jorge ; Adelson, P. David ; Weiner, Howard L. ; Gandhi, Roopali ; Goilav, Beatrice ; Putterman, Chaim ; Saugstad, Julie A.</creator><creatorcontrib>Quinn, Joseph F. ; Patel, Tushar ; Wong, David ; Das, Saumya ; Freedman, Jane E. ; Laurent, Louise C. ; Carter, Bob S. ; Hochberg, Fred ; Keuren-Jensen, Kendall Van ; Huentelman, Matt ; Spetzler, Robert ; S. Kalani, M. Yashar ; Arango, Jorge ; Adelson, P. David ; Weiner, Howard L. ; Gandhi, Roopali ; Goilav, Beatrice ; Putterman, Chaim ; Saugstad, Julie A.</creatorcontrib><description>Ten ongoing studies designed to test the possibility that extracellular RNAs may serve as biomarkers in human disease are described. These studies, funded by the NIH Common Fund Extracellular RNA Communication Program, examine diverse extracellular body fluids, including plasma, serum, urine and cerebrospinal fluid. The disorders studied include hepatic and gastric cancer, cardiovascular disease, chronic kidney disease, neurodegenerative disease, brain tumours, intracranial haemorrhage, multiple sclerosis and placental disorders. Progress to date and the plans for future studies are outlined.</description><identifier>ISSN: 2001-3078</identifier><identifier>EISSN: 2001-3078</identifier><identifier>DOI: 10.3402/jev.v4.27495</identifier><identifier>PMID: 26320940</identifier><language>eng</language><publisher>Sweden: Taylor & Francis</publisher><subject>Alzheimer's disease ; Biomarkers ; Body fluids ; Brain tumors ; Cardiovascular diseases ; Cell cycle ; Cerebrospinal fluid ; Colleges & universities ; Consortia ; Disease ; ERCC ; exRNA ; extracellular RNA ; Funding ; Gastric cancer ; Hemorrhage ; Hypothesis testing ; Ischemia ; Kidney diseases ; Learned societies ; Liver cancer ; Liver cirrhosis ; Liver diseases ; Lupus ; MicroRNAs ; Mortality ; Multiple sclerosis ; Nervous system ; Neurodegenerative diseases ; Pediatrics ; Plasma ; Prostate cancer ; Proteins ; Special Issue: Extracellular RNA Communication Consortium</subject><ispartof>Journal of extracellular vesicles, 2015-01, Vol.4 (1), p.27495-n/a</ispartof><rights>2015 Joseph F. Quinn et al. 2015</rights><rights>2015 Joseph F. Quinn et al.</rights><rights>Copyright Co-Action Publishing 2015</rights><rights>2015. This work is published under http://creativecommons.org/licenses/by-nc/4.0/ (the "License"). Notwithstanding the ProQuest Terms and Conditions, you may use this content in accordance with the terms of the License.</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c6337-fc07a174cb8c594aea34930bdeacb923b1d6d1f14cfee11e53186eb18a14abc23</citedby><cites>FETCH-LOGICAL-c6337-fc07a174cb8c594aea34930bdeacb923b1d6d1f14cfee11e53186eb18a14abc23</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC4553262/pdf/$$EPDF$$P50$$Gpubmedcentral$$Hfree_for_read</linktopdf><linktohtml>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC4553262/$$EHTML$$P50$$Gpubmedcentral$$Hfree_for_read</linktohtml><link.rule.ids>230,314,727,780,784,864,885,1417,2102,4139,11562,27502,27924,27925,45574,45575,46052,46476,53791,53793,59143,59144</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/26320940$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Quinn, Joseph F.</creatorcontrib><creatorcontrib>Patel, Tushar</creatorcontrib><creatorcontrib>Wong, David</creatorcontrib><creatorcontrib>Das, Saumya</creatorcontrib><creatorcontrib>Freedman, Jane E.</creatorcontrib><creatorcontrib>Laurent, Louise C.</creatorcontrib><creatorcontrib>Carter, Bob S.</creatorcontrib><creatorcontrib>Hochberg, Fred</creatorcontrib><creatorcontrib>Keuren-Jensen, Kendall Van</creatorcontrib><creatorcontrib>Huentelman, Matt</creatorcontrib><creatorcontrib>Spetzler, Robert</creatorcontrib><creatorcontrib>S. Kalani, M. Yashar</creatorcontrib><creatorcontrib>Arango, Jorge</creatorcontrib><creatorcontrib>Adelson, P. David</creatorcontrib><creatorcontrib>Weiner, Howard L.</creatorcontrib><creatorcontrib>Gandhi, Roopali</creatorcontrib><creatorcontrib>Goilav, Beatrice</creatorcontrib><creatorcontrib>Putterman, Chaim</creatorcontrib><creatorcontrib>Saugstad, Julie A.</creatorcontrib><title>Extracellular RNAs: development as biomarkers of human disease</title><title>Journal of extracellular vesicles</title><addtitle>J Extracell Vesicles</addtitle><description>Ten ongoing studies designed to test the possibility that extracellular RNAs may serve as biomarkers in human disease are described. These studies, funded by the NIH Common Fund Extracellular RNA Communication Program, examine diverse extracellular body fluids, including plasma, serum, urine and cerebrospinal fluid. The disorders studied include hepatic and gastric cancer, cardiovascular disease, chronic kidney disease, neurodegenerative disease, brain tumours, intracranial haemorrhage, multiple sclerosis and placental disorders. Progress to date and the plans for future studies are outlined.</description><subject>Alzheimer's disease</subject><subject>Biomarkers</subject><subject>Body fluids</subject><subject>Brain tumors</subject><subject>Cardiovascular diseases</subject><subject>Cell cycle</subject><subject>Cerebrospinal fluid</subject><subject>Colleges & universities</subject><subject>Consortia</subject><subject>Disease</subject><subject>ERCC</subject><subject>exRNA</subject><subject>extracellular RNA</subject><subject>Funding</subject><subject>Gastric cancer</subject><subject>Hemorrhage</subject><subject>Hypothesis testing</subject><subject>Ischemia</subject><subject>Kidney diseases</subject><subject>Learned societies</subject><subject>Liver cancer</subject><subject>Liver cirrhosis</subject><subject>Liver diseases</subject><subject>Lupus</subject><subject>MicroRNAs</subject><subject>Mortality</subject><subject>Multiple sclerosis</subject><subject>Nervous system</subject><subject>Neurodegenerative diseases</subject><subject>Pediatrics</subject><subject>Plasma</subject><subject>Prostate cancer</subject><subject>Proteins</subject><subject>Special Issue: Extracellular RNA Communication Consortium</subject><issn>2001-3078</issn><issn>2001-3078</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2015</creationdate><recordtype>article</recordtype><sourceid>0YH</sourceid><sourceid>24P</sourceid><sourceid>WIN</sourceid><sourceid>AFKRA</sourceid><sourceid>AZQEC</sourceid><sourceid>BENPR</sourceid><sourceid>CCPQU</sourceid><sourceid>DWQXO</sourceid><sourceid>GNUQQ</sourceid><sourceid>DOA</sourceid><recordid>eNqNkktv1DAUhSMEolXpjjWKxIYFM_gZOywqlWoKRRVICNhaN_ZNmyGJBztJmX-PpylVi1CFN359Prr3-GTZc0qWXBD2Zo3TchJLpkQpH2X7jBC64ETpx3fWe9lhjGuSRimo1OXTbI8VnKUd2c-OVr-GABbbdmwh5F8-Hce3ucMJW7_psB9yiHnV-A7CDwwx93V-OXbQ566JCBGfZU9qaCMe3swH2bfT1deTD4vzz-_PTo7PF7bgXC1qSxRQJWylrSwFIHBRclI5BFuVjFfUFY7WVNgakVKUnOoCK6qBCqgs4wfZ2azrPKzNJjSpoK3x0JjrAx8uDIShsS0a6hjXlDsrhBQVq0E4yUuqnNVOFKpMWkez1masOnQ2dRmgvSd6_6ZvLs2Fn4yQkrNiV8yrG4Hgf44YB9M1cWch9OjHaKhKrWpN1P-gROtSSaUT-vIvdO3H0CdXDSfJIyHTBz5EJa1SiGTsTuv1TNngYwxY33ZHidkFx6TgmEmY6-Ak_MVdR27hPzFJgJyBq6bF7YNi5uPqO3t3mtLGVXqn5ndNX_vQwZUPrTMDbFsf6gC9bVJz_yzpN6RO4IY</recordid><startdate>201501</startdate><enddate>201501</enddate><creator>Quinn, Joseph F.</creator><creator>Patel, Tushar</creator><creator>Wong, David</creator><creator>Das, Saumya</creator><creator>Freedman, Jane E.</creator><creator>Laurent, Louise C.</creator><creator>Carter, Bob S.</creator><creator>Hochberg, Fred</creator><creator>Keuren-Jensen, Kendall Van</creator><creator>Huentelman, Matt</creator><creator>Spetzler, Robert</creator><creator>S. 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| source | Wiley Journals; DOAJ Directory of Open Access Journals; Co-Action Open Access Journals; Wiley Online Library Open Access; Access via Taylor & Francis (Open Access Collection); EZB-FREE-00999 freely available EZB journals; PubMed Central |
| subjects | Alzheimer's disease Biomarkers Body fluids Brain tumors Cardiovascular diseases Cell cycle Cerebrospinal fluid Colleges & universities Consortia Disease ERCC exRNA extracellular RNA Funding Gastric cancer Hemorrhage Hypothesis testing Ischemia Kidney diseases Learned societies Liver cancer Liver cirrhosis Liver diseases Lupus MicroRNAs Mortality Multiple sclerosis Nervous system Neurodegenerative diseases Pediatrics Plasma Prostate cancer Proteins Special Issue: Extracellular RNA Communication Consortium |
| title | Extracellular RNAs: development as biomarkers of human disease |
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