Simultaneous estimation of metoprolol succinate and chlorthalidone in pharmaceutical solid dosage form by using a developed and validated reverse phase high performance liquid chromatographic technique

The separation of both the drugs was achieved on Inertsil ODS 3 column (100 × 4.6 mm, 5 μm) column using a mobile phase of diammonium hydrogen phosphate buffer solution (at pH 5.5): Methanol (70:30 v/v). The flow rate was 1.0 ml/min and detection was done at 254 nm. The retention time for metoprolol...

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Veröffentlicht in:	Scholars research journal 2012, Vol.2 (1), p.17
Hauptverfasser:	Sheth, Avani, Patel, ChhaganN, Ramlingam, Badmanaban, Shah, Nehal
Format:	Artikel
Sprache:	eng
Schlagworte:	Accuracy Calibration Chromatography Drug dosages Hypertension Literature reviews Mass spectrometry Methods Pharmaceuticals Standard deviation
Online-Zugang:	Volltext
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