Neutrons in studies of phospholipid bilayers and bilayer–drug interaction. II. Small-angle scattering
In this paper, we demonstrate several possibilities of using neutron scattering in pharmaceutical research based on examples of scientific results achieved at our University. In this second part, elementary principles of small-angle neutron scattering and simple methods of scattering data evaluation...
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Veröffentlicht in: | Acta Facultatis Pharmaceuticae Universitatis Comenianae 2014-12, Vol.61 (2), p.12-20 |
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container_title | Acta Facultatis Pharmaceuticae Universitatis Comenianae |
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creator | Belička, M. Devínsky, F. Balgavý, P. |
description | In this paper, we demonstrate several possibilities of using neutron scattering in pharmaceutical research based on examples of
scientific results achieved at our University. In this second part, elementary principles of small-angle neutron scattering and simple
methods of scattering data evaluation are described. Results of scattering on bilayers in unilamellar liposomes with intercalated
general anaesthetics, antimicrobials or cholesterol demonstrate the potential of this method at determination of structural properties
of bilayers. |
doi_str_mv | 10.2478/afpuc-2014-0011 |
format | Article |
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methods of scattering data evaluation are described. Results of scattering on bilayers in unilamellar liposomes with intercalated
general anaesthetics, antimicrobials or cholesterol demonstrate the potential of this method at determination of structural properties
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scientific results achieved at our University. In this second part, elementary principles of small-angle neutron scattering and simple
methods of scattering data evaluation are described. Results of scattering on bilayers in unilamellar liposomes with intercalated
general anaesthetics, antimicrobials or cholesterol demonstrate the potential of this method at determination of structural properties
of bilayers.</description><subject>alkan-1-ol</subject><subject>alkanes</subject><subject>cholesterol</subject><subject>Drug therapy</subject><subject>lipid bilayer</subject><subject>Lipids</subject><subject>neutron scattering</subject><subject>Neutrons</subject><subject>phospholipid liposomes</subject><subject>Phosphorus content</subject><subject>Scattering</subject><issn>1338-6786</issn><issn>1338-6786</issn><issn>2453-6725</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2014</creationdate><recordtype>article</recordtype><sourceid>ABUWG</sourceid><sourceid>AFKRA</sourceid><sourceid>AZQEC</sourceid><sourceid>BENPR</sourceid><sourceid>CCPQU</sourceid><sourceid>DWQXO</sourceid><recordid>eNptUE1LAzEQDaJgqT17DXjeNh-72V3wIkVtoehBPYc0mawp29012UV68z_4D_0lplakBweGecPMe8M8hC4pmbI0L2bKdoNOGKFpQgilJ2hEOS8SkRfi9Aifo0kIGxJDMJGlYoSqBxh63zYBuwaHfjAOAm4t7l7bELN2nTN47Wq1Ax-wav6ar49P44cq0nrwSveubaZ4uZzip62q60Q1VQ04aNXHsWuqC3RmVR1g8lvH6OXu9nm-SFaP98v5zSrRjDOWWCgNcCCpyQTnjAsGomSKgCmUzsw6zRWjOUtLW-pCGQZgaZZpqnVqrSU5H6Org27n27cBQi837eCbeFJSURY0K_OCxq3ZYUv7NgQPVnbebZXfSUrk3lD5Y6jcGyr3hkbG9YHxrur4kYHKD7sIjuT_ZwrKKOPfDfOADw</recordid><startdate>20141230</startdate><enddate>20141230</enddate><creator>Belička, M.</creator><creator>Devínsky, F.</creator><creator>Balgavý, P.</creator><general>De Gruyter Open</general><general>De Gruyter Poland</general><scope>AAYXX</scope><scope>CITATION</scope><scope>3V.</scope><scope>7X7</scope><scope>7XB</scope><scope>8AO</scope><scope>8C1</scope><scope>8FI</scope><scope>8FJ</scope><scope>8FK</scope><scope>ABUWG</scope><scope>AFKRA</scope><scope>AZQEC</scope><scope>BENPR</scope><scope>BYOGL</scope><scope>CCPQU</scope><scope>DWQXO</scope><scope>FYUFA</scope><scope>GHDGH</scope><scope>K9.</scope><scope>M0S</scope><scope>PIMPY</scope><scope>PQEST</scope><scope>PQQKQ</scope><scope>PQUKI</scope><scope>PRINS</scope></search><sort><creationdate>20141230</creationdate><title>Neutrons in studies of phospholipid bilayers and bilayer–drug interaction. 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II. Small-angle scattering</atitle><jtitle>Acta Facultatis Pharmaceuticae Universitatis Comenianae</jtitle><date>2014-12-30</date><risdate>2014</risdate><volume>61</volume><issue>2</issue><spage>12</spage><epage>20</epage><pages>12-20</pages><issn>1338-6786</issn><eissn>1338-6786</eissn><eissn>2453-6725</eissn><abstract>In this paper, we demonstrate several possibilities of using neutron scattering in pharmaceutical research based on examples of
scientific results achieved at our University. In this second part, elementary principles of small-angle neutron scattering and simple
methods of scattering data evaluation are described. Results of scattering on bilayers in unilamellar liposomes with intercalated
general anaesthetics, antimicrobials or cholesterol demonstrate the potential of this method at determination of structural properties
of bilayers.</abstract><cop>Bratislava</cop><pub>De Gruyter Open</pub><doi>10.2478/afpuc-2014-0011</doi><tpages>9</tpages><oa>free_for_read</oa></addata></record> |
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source | ProQuest Central (Alumni Edition); DOAJ Directory of Open Access Journals; Walter De Gruyter: Open Access Journals; ProQuest Central UK/Ireland; ProQuest Central |
subjects | alkan-1-ol alkanes cholesterol Drug therapy lipid bilayer Lipids neutron scattering Neutrons phospholipid liposomes Phosphorus content Scattering |
title | Neutrons in studies of phospholipid bilayers and bilayer–drug interaction. II. Small-angle scattering |
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