Salivary Thromboxane A2-Binding Proteins from Triatomine Vectors of Chagas Disease Inhibit Platelet-Mediated Neutrophil Extracellular Traps (NETs) Formation and Arterial Thrombosis: e0003869

Background The saliva of blood-feeding arthropods contains a notable diversity of molecules that target the hemostatic and immune systems of the host. Dipetalodipin and triplatin are triatomine salivary proteins that exhibit high affinity binding to prostanoids, such as TXA2, thus resulting in poten...

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Veröffentlicht in:	PLoS neglected tropical diseases 2015-06, Vol.9 (6)
Hauptverfasser:	Mizurini, Daniella M, Aslan, Jorgeane S, Gomes, Tainá, Ma, Dongying, Francischetti, Ivo MB, Monteiro, Robson Q
Format:	Artikel
Sprache:	eng
Schlagworte:	Blood Blood clots Blood platelets Carotid arteries Collagen Disease Extracellular matrix Immune system Proteins Studies Thromboembolism Thrombosis Tropical diseases Vector-borne diseases
Online-Zugang:	Volltext
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