Contact between the [beta]1 and [beta]2 Segments of [alpha]-Synuclein that Inhibits Amyloid Formation

Conversion of the intrinsically disordered protein [alpha]-synuclein ([alpha]-syn) into amyloid aggregates is a key process in Parkinson's disease. The sequence region 35-59 contains [beta]-strand segments [beta]1 and [beta]2 of [alpha]-syn amyloid fibril models and most disease-related mutatio...

Ausführliche Beschreibung

Bibliographische Detailangaben

Veröffentlicht in:	Angewandte Chemie International Edition 2015-07, Vol.54 (30), p.8837
Hauptverfasser:	Shaykhalishahi, Hamed, Gauhar, Aziz, Wordehoff, Michael M, Gruning, Clara S R, Klein, Antonia N, Bannach, Oliver, Stoldt, Matthias, Willbold, Dieter, Hard, Torleif, Hoyer, Wolfgang
Format:	Artikel
Sprache:	eng
Schlagworte:	Alzheimer's disease
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!