Statins and Aspirin: Do They Really Work in Women?
Cardiovascular disease continues to be the most common cause of mortality in women in the USA. As a result, greater emphasis has been placed on preventive measures. Studies examining the role of aspirin and HMG-CoA reductase inhibitors (statins) have shown important clinical differences in men versu...
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| Veröffentlicht in: | American journal of cardiovascular drugs : drugs, devices, and other interventions devices, and other interventions, 2015-06, Vol.15 (3), p.151-162 |
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| container_title | American journal of cardiovascular drugs : drugs, devices, and other interventions |
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| creator | Desai, Hemal Hollingsworth, Paula W. Chugh, Atul R. |
| description | Cardiovascular disease continues to be the most common cause of mortality in women in the USA. As a result, greater emphasis has been placed on preventive measures. Studies examining the role of aspirin and HMG-CoA reductase inhibitors (statins) have shown important clinical differences in men versus women in the preventive realm. This has led to inconsistent recommendations by guideline committees and clinicians alike. This review presents a summary of the past and current guidelines. In addition, important clinical trials influencing current era practice are also discussed. Both strengths and limitations of these studies are described in detail, along with recommendations regarding future directions and the scope of aspirin and statin use for primary and secondary prevention of cardiovascular disease. |
| doi_str_mv | 10.1007/s40256-015-0111-x |
| format | Article |
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| ispartof | American journal of cardiovascular drugs : drugs, devices, and other interventions, 2015-06, Vol.15 (3), p.151-162 |
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| language | eng |
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| source | MEDLINE; Springer Nature - Complete Springer Journals |
| subjects | Aspirin - therapeutic use Cardiology Cardiovascular Diseases - mortality Cardiovascular Diseases - prevention & control Female Humans Hydroxymethylglutaryl-CoA Reductase Inhibitors - therapeutic use Leading Article Male Medicine Medicine & Public Health Pharmacology/Toxicology Pharmacotherapy Platelet Aggregation Inhibitors - therapeutic use Practice Guidelines as Topic Primary Prevention - methods Secondary Prevention - methods Sex Factors |
| title | Statins and Aspirin: Do They Really Work in Women? |
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