Rhinoscleroma
A 63-year-old man presented with a 10-year history of a mass growing in the central region of his face, involving his nose and upper lip. Histopathological examination revealed foamy macrophages, and culture of tissue fragments showed the presence of klebsiella. A 63-year-old man presented with a 10...
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| Veröffentlicht in: | The New England journal of medicine 2015-06, Vol.372 (25), p.e33 |
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| creator | Castanedo Cázares, Juan P Martinez Rosales, Karla I |
| description | A 63-year-old man presented with a 10-year history of a mass growing in the central region of his face, involving his nose and upper lip. Histopathological examination revealed foamy macrophages, and culture of tissue fragments showed the presence of klebsiella.
A 63-year-old man presented with a 10-year history of a mass growing in the central region of his face, involving his nose and upper lip. He had lived his entire life in an isolated tropical region of Mexico and had received no previous treatment for this condition. Physical examination revealed a systemically well man with bilateral nostril obliteration, palate infiltration, and loss of upper teeth (Panel A). Histopathological examination revealed foamy macrophages (Mikulicz’s cells; Panel B, yellow arrow; hematoxylin and eosin) with intracytoplasmic bacilli plasma cells with Russell bodies (green arrow). Culture of tissue fragments showed the presence of klebsiella. . . . |
| doi_str_mv | 10.1056/NEJMicm1411602 |
| format | Article |
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A 63-year-old man presented with a 10-year history of a mass growing in the central region of his face, involving his nose and upper lip. He had lived his entire life in an isolated tropical region of Mexico and had received no previous treatment for this condition. Physical examination revealed a systemically well man with bilateral nostril obliteration, palate infiltration, and loss of upper teeth (Panel A). Histopathological examination revealed foamy macrophages (Mikulicz’s cells; Panel B, yellow arrow; hematoxylin and eosin) with intracytoplasmic bacilli plasma cells with Russell bodies (green arrow). Culture of tissue fragments showed the presence of klebsiella. . . .</description><identifier>ISSN: 0028-4793</identifier><identifier>EISSN: 1533-4406</identifier><identifier>DOI: 10.1056/NEJMicm1411602</identifier><language>eng</language><publisher>Boston: Massachusetts Medical Society</publisher><subject>Case reports ; Macrophages ; Nose ; Rhinoscleroma ; Tissue culture</subject><ispartof>The New England journal of medicine, 2015-06, Vol.372 (25), p.e33</ispartof><rights>Copyright © 2015 Massachusetts Medical Society. All rights reserved.</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c368t-3b757d2b0d46dcc3e86f75623ffd9b2e2a09db668da9f0ed741c6623b56787033</citedby></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://www.nejm.org/doi/pdf/10.1056/NEJMicm1411602$$EPDF$$P50$$Gmms$$H</linktopdf><linktohtml>$$Uhttps://www.nejm.org/doi/full/10.1056/NEJMicm1411602$$EHTML$$P50$$Gmms$$H</linktohtml><link.rule.ids>314,776,780,2746,2747,26080,27901,27902,52357,54039</link.rule.ids></links><search><creatorcontrib>Castanedo Cázares, Juan P</creatorcontrib><creatorcontrib>Martinez Rosales, Karla I</creatorcontrib><title>Rhinoscleroma</title><title>The New England journal of medicine</title><description>A 63-year-old man presented with a 10-year history of a mass growing in the central region of his face, involving his nose and upper lip. Histopathological examination revealed foamy macrophages, and culture of tissue fragments showed the presence of klebsiella.
A 63-year-old man presented with a 10-year history of a mass growing in the central region of his face, involving his nose and upper lip. He had lived his entire life in an isolated tropical region of Mexico and had received no previous treatment for this condition. Physical examination revealed a systemically well man with bilateral nostril obliteration, palate infiltration, and loss of upper teeth (Panel A). Histopathological examination revealed foamy macrophages (Mikulicz’s cells; Panel B, yellow arrow; hematoxylin and eosin) with intracytoplasmic bacilli plasma cells with Russell bodies (green arrow). Culture of tissue fragments showed the presence of klebsiella. . . .</description><subject>Case reports</subject><subject>Macrophages</subject><subject>Nose</subject><subject>Rhinoscleroma</subject><subject>Tissue culture</subject><issn>0028-4793</issn><issn>1533-4406</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2015</creationdate><recordtype>article</recordtype><sourceid>BEC</sourceid><sourceid>BENPR</sourceid><sourceid>GUQSH</sourceid><sourceid>M2O</sourceid><recordid>eNp1jztPw0AQhE8IJExIyx9AonPYe-3dlSgKBBRAQlCf7HsIW7Ed7pKCf48j01CwzRT7zYyGkCsKCwoSb19WT8-N66igFIGdkIJKzkshAE9JAcB0KZTh5-Qi5xbGo8IUZP722fRDdtuQhq66JGex2uYw_9UZ-bhfvS_X5eb14XF5tykdR70vea2k8qwGL9A7x4PGqCQyHqM3NQusAuNrRO0rEyF4JajD8V1LVFoB5zNyPeXu0vB1CHlv2-GQ-rHSUtRGI0p6pBYT5dKQcwrR7lLTVenbUrDHyfbv5NFwMxm6Lts-tN1_4A9SilL0</recordid><startdate>20150618</startdate><enddate>20150618</enddate><creator>Castanedo Cázares, Juan P</creator><creator>Martinez Rosales, Karla I</creator><general>Massachusetts Medical Society</general><scope>AAYXX</scope><scope>CITATION</scope><scope>0TZ</scope><scope>7RV</scope><scope>7X7</scope><scope>7XB</scope><scope>8AO</scope><scope>8C1</scope><scope>8FE</scope><scope>8FH</scope><scope>8FI</scope><scope>ABUWG</scope><scope>AFKRA</scope><scope>AN0</scope><scope>AZQEC</scope><scope>BBNVY</scope><scope>BEC</scope><scope>BENPR</scope><scope>BHPHI</scope><scope>CCPQU</scope><scope>DWQXO</scope><scope>FYUFA</scope><scope>GHDGH</scope><scope>GNUQQ</scope><scope>GUQSH</scope><scope>HCIFZ</scope><scope>K0Y</scope><scope>LK8</scope><scope>M0R</scope><scope>M0T</scope><scope>M1P</scope><scope>M2M</scope><scope>M2O</scope><scope>M2P</scope><scope>M7P</scope><scope>MBDVC</scope><scope>NAPCQ</scope><scope>PQEST</scope><scope>PQQKQ</scope><scope>PQUKI</scope><scope>PRINS</scope><scope>PSYQQ</scope><scope>Q9U</scope></search><sort><creationdate>20150618</creationdate><title>Rhinoscleroma</title><author>Castanedo Cázares, Juan P ; 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Histopathological examination revealed foamy macrophages, and culture of tissue fragments showed the presence of klebsiella.
A 63-year-old man presented with a 10-year history of a mass growing in the central region of his face, involving his nose and upper lip. He had lived his entire life in an isolated tropical region of Mexico and had received no previous treatment for this condition. Physical examination revealed a systemically well man with bilateral nostril obliteration, palate infiltration, and loss of upper teeth (Panel A). Histopathological examination revealed foamy macrophages (Mikulicz’s cells; Panel B, yellow arrow; hematoxylin and eosin) with intracytoplasmic bacilli plasma cells with Russell bodies (green arrow). Culture of tissue fragments showed the presence of klebsiella. . . .</abstract><cop>Boston</cop><pub>Massachusetts Medical Society</pub><doi>10.1056/NEJMicm1411602</doi></addata></record> |
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| ispartof | The New England journal of medicine, 2015-06, Vol.372 (25), p.e33 |
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| language | eng |
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| subjects | Case reports Macrophages Nose Rhinoscleroma Tissue culture |
| title | Rhinoscleroma |
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