Molecular Evolution of Broadly Neutralizing Llama Antibodies to the CD4-Binding Site of HIV-1: e1004552

To date, no immunization of humans or animals has elicited broadly neutralizing sera able to prevent HIV-1 transmission; however, elicitation of broad and potent heavy chain only antibodies (HCAb) has previously been reported in llamas. In this study, the anti-HIV immune responses in immunized llama...

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Veröffentlicht in:	PLoS pathogens 2014-12, Vol.10 (12)
Hauptverfasser:	McCoy, Laura E, Rutten, Lucy, Frampton, Dan, Anderson, Ian, Granger, Luke, Bashford-Rogers, Rachael, Dekkers, Gillian, Strokappe, Nika M, Seaman, Michael S, Koh, Willie, Grippo, Vanina, Kliche, Alexander, Verrips, Theo, Kellam, Paul, Fassati, Ariberto, Weiss, Robin A
Format:	Artikel
Sprache:	eng
Schlagworte:	Acquired immune deficiency syndrome AIDS Animals Immunization Infections Methods Neutralization Vaccines
Online-Zugang:	Volltext
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