Drosophila TIM Binds Importin [alpha]1, and Acts as an Adapter to Transport PER to the Nucleus: e1004974

Regulated nuclear entry of clock proteins is a conserved feature of eukaryotic circadian clocks and serves to separate the phase of mRNA activation from mRNA repression in the molecular feedback loop. In Drosophila, nuclear entry of the clock proteins, PERIOD (PER) and TIMELESS (TIM), is tightly con...

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Veröffentlicht in:PLoS genetics 2015-02, Vol.11 (2)
Hauptverfasser: Jang, A Reum, Moravcevic, Katarina, Saez, Lino, Young, Michael W, Sehgal, Amita
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Sprache:eng
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