The Development of a Versatile Trifunctional Scaffold for Biological Applications

We describe the synthesis of a trifunctional scaffold constructed from a planar core of trimesic acid derivatized with three propargylamine moieties. The scaffold was attached to a solid‐phase resin through the carboxylic group of a fluorinated alkyl spacer arm. The orthogonal protection of two of t...

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Veröffentlicht in:	European journal of organic chemistry 2015-06, Vol.2015 (17), p.3689-3701
Hauptverfasser:	Vaněk, Václav, Pícha, Jan, Fabre, Benjamin, Buděšínský, Miloš, Lepšík, Martin, Jiráček, Jiří
Format:	Artikel
Sprache:	eng
Schlagworte:	Alkynes Azides Click chemistry Copper Protein mimics Solid-phase synthesis Solids
Online-Zugang:	Volltext
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