Angiopoietin-1 Protects the Endothelial Cells Against Advanced Glycation End Product Injury by Strengthening Cell Junctions and Inhibiting Cell Apoptosis

Endothelial dysfunction is a major characteristic of diabetic vasculopathy. Protection of the vascular endothelium is an essential aspect of preventing and treating diabetic vascular complications. Although Angiopoietin‐1 (Ang‐1) is an important endothelial‐specific protective factor, whether Ang‐1...

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Veröffentlicht in:	Journal of cellular physiology 2015-08, Vol.230 (8), p.1895-1905
Hauptverfasser:	Zhao, Jingling, Chen, Lei, Shu, Bin, Tang, Jinming, Zhang, Lijun, Xie, Julin, Liu, Xusheng, Xu, Yingbin, Qi, Shaohai
Format:	Artikel
Sprache:	eng
Schlagworte:	Angiopoietin-1 - metabolism Angiopoietin-1 - pharmacology Apoptosis - drug effects Apoptosis - physiology Blotting, Western Capillary Permeability - drug effects Capillary Permeability - physiology Cell Line Endothelial Cells - pathology Fluorescent Antibody Technique Gene Knockdown Techniques Glycation End Products, Advanced - toxicity Humans Immunoprecipitation In Situ Nick-End Labeling Intercellular Junctions - drug effects Intercellular Junctions - metabolism
Online-Zugang:	Volltext
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