'Cryptococcus neoformans' infection among human immunodeficiency virus patients on highly active antiretroviral therapy in Benin City, Nigeria

'Cryptococcus neoformans' infection among human immunodeficiency virus patients on highly active antiretroviral therapy in Benin City, Nigeria

Objective: Cryptococcus neoformans infection is a well-recognized AIDS defining illness among HIV patients. Against the background of no data on C. neoformans infection among HIV patients in Nigeria, we determined its prevalence among HIV patients on highly active antiretroviral therapy (HAART). Met...

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Veröffentlicht in:New Zealand journal of medical laboratory science 2015-04, Vol.69 (1), p.21-23
Hauptverfasser: Egbe, Christopher A, Omoregie, Richard, Alex-Ighodalo, Otibhor
Format: Artikel
Sprache:eng
Schlagworte:
Cryptococcus neoformans
Distribution
Forecasts and trends
Health aspects
Highly active antiretroviral therapy
HIV infections
HIV patients
Medical statistics
Mycoses
Treatment
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Zusammenfassung:Objective: Cryptococcus neoformans infection is a well-recognized AIDS defining illness among HIV patients. Against the background of no data on C. neoformans infection among HIV patients in Nigeria, we determined its prevalence among HIV patients on highly active antiretroviral therapy (HAART). Methods: Blood samples were collected from 333 HIV patients on HAART (156 males; 177 females) and analysed for cryptococcal capsular antigen and CD4 count using standard techniques. Results: Gender was not a significant risk factor for acquiring cryptococcal infection (OR = 1.40; 95%CI: 0.67-2.92, P = 0.471). The prevalence of cryptococcal infection was not significantly affected by age (P = 0.302). A CD4 count of
ISSN:1171-0195