Inhibitory effects of indole [alpha]-lipoic acid derivatives on nitric oxide production in LPS/IFN[gamma] activated RAW 264.7 macrophages

Alpha-lipoic acid ([alpha]-lipoic acid) is a potent antioxidant compound that has been shown to possess anti-inflammatory effects. RAW 264.7 macrophages produce various inflammatory mediators such as nitric oxide, IL-1[beta], IL-6 and TNF-alpha upon activation with LPS ( Lipopolysaccharide) and IFN[...

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Veröffentlicht in:Cell biochemistry and function 2015-04, Vol.33 (3), p.121
Hauptverfasser: Karabay, Arzu Zeynep, Koc, Asli, Gurkan-Alp, A Selen, Buyukbingol, Zeliha, Buyukbingol, Erdem
Format: Artikel
Sprache:eng
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