Stereoselective Total Synthesis of Crassalactone A, a Natural Cytotoxic Styryl Lactone

A stereoselective total synthesis of a naturally occurring cytotoxic styryl lactone, crassalactone A (1), has been accomplished. The synthesis involves (−)‐diisopropyl D‐tartrate as the starting material, and the stereoselective additions of Grignard reagent and MeNO2 to two chiral aldehyde intermed...

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Veröffentlicht in:	Helvetica chimica acta 2015-04, Vol.98 (4), p.509-514
Hauptverfasser:	Raghavendar Reddy, Parigi, Das, Biswanath
Format:	Artikel
Sprache:	eng
Schlagworte:	(−)-Diisopropyl D-tartrate Crassalactone A Cytotoxicity Grignard reaction Methane Methane, nitro nitro
Online-Zugang:	Volltext
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