Characterization of anticonvulsant and antiepileptogenic potential of thymol in various experimental models

The present study was to investigate the anticonvulsant and antiepileptogenic potential of thymol. Anticonvulsant activity of thymol (5–100 mg/kg i.p.) was studied using maximal electroshock, pentylenetetrazole (PTZ), strychnine and 4-aminopyridine (4-AP) models. Thymol at the selected dose was also...

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Veröffentlicht in:	Naunyn-Schmiedeberg's archives of pharmacology 2014, Vol.387 (1), p.59-66
Hauptverfasser:	Sancheti, Jayant, Shaikh, Mohd Farooq, Chaudhari, Rahul, Somani, Gauresh, Patil, Sachin, Jain, Pankaj, Sathaye, Sadhana
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Anticonvulsants - therapeutic use Biomedical and Life Sciences Biomedicine Disease Models, Animal Dose-Response Relationship, Drug Male Mice Neurosciences Original Article Pentylenetetrazole - toxicity Pharmacology/Toxicology Rats Rats, Wistar Seizures - chemically induced Seizures - drug therapy Seizures - physiopathology Thymol - therapeutic use
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