Influence of phosphodiesterases and cGMP on cAMP generation and on phosphorylation of phospholamban and troponin I by 5-HT^sub 4^ receptor activation in porcine left atrium

Our objective was to investigate the role of phosphodiesterase (PDE)3 and PDE4 and cGMP in the control of cAMP metabolism and of phosphorylation of troponin I (TnI) and phospholamban (PLB) when 5-HT^sub 4^ receptors are activated in pig left atrium. Electrically paced porcine left atrial muscles, mo...

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Veröffentlicht in:Naunyn-Schmiedeberg's archives of pharmacology 2013-08, Vol.386 (8), p.671
Hauptverfasser: Weninger, Sabine, De Maeyer, Joris H, Lefebvre, Romain A
Format: Artikel
Sprache:eng
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