Target-Based Whole-Cell Screening by 1HNMR Spectroscopy

An NMR-based approach marries the two traditional screening technologies (phenotypic and target-based screening) to find compounds inhibiting a specific enzymatic reaction in bacterial cells. Building on a previous study in which it was demonstrated that hydrolytic decomposition of meropenem in livi...

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Veröffentlicht in:	Angewandte Chemie International Edition 2015-04, Vol.54 (16), p.4764
Hauptverfasser:	Ma, Junhe, Cao, Qing, McLeod, Sarah M, Ferguson, Keith, Gao, Ning, Breeze, Alexander L, Hu, Jun
Format:	Artikel
Sprache:	eng
Online-Zugang:	Volltext
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