Differential organ phenotypes after postnatal Igf1r gene conditional deletion induced by tamoxifen in UBC-CreERT2; Igf1r^sup fl/fl^ double transgenic mice

Insulin-like growth factor type 1 receptor (IGF1R) is a ubiquitously expressed tyrosine kinase that regulates cell proliferation, differentiation and survival. It controls body growth and organ homeostasis, but with specific functions depending on developmental time and cell type. Human deficiency i...

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Veröffentlicht in:	Transgenic research 2015-04, Vol.24 (2), p.279
Hauptverfasser:	López, Icíar Paula, Rodriguez-de la Rosa, Lourdes, Pais, Rosete Sofia, Piñeiro-hermida, Sergio, Torrens, Raquel, Contreras, Julio, Varela-nieto, Isabel, Pichel, José García
Format:	Artikel
Sprache:	eng
Online-Zugang:	Volltext
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