Multiple daily doses of acetyl‐salicylic acid (ASA) overcome reduced platelet response to once‐daily ASA after coronary artery bypass graft surgery: a pilot randomized controlled trial

Summary Background The efficacy of ASA for prevention of graft failure following CABG surgery may be limited by incomplete platelet inhibition due to increased post‐operative platelet turnover. Objectives To determine whether acetyl‐salicylic acid (ASA) 325 mg once‐daily or 81 mg four‐times daily ov...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	Journal of thrombosis and haemostasis 2015-03, Vol.13 (3), p.448-456
Hauptverfasser:	Paikin, J. S., Hirsh, J., Ginsberg, J. S., Weitz, J. I., Chan, N. C., Whitlock, R. P., Pare, G., Johnston, M., Eikelboom, J. W.
Format:	Artikel
Sprache:	eng
Schlagworte:	Aged aspirin Aspirin - administration & dosage Aspirin - adverse effects Biomarkers - blood Blood Platelets - drug effects Blood Platelets - metabolism coronary artery bypass Coronary Artery Bypass - adverse effects Drug Administration Schedule Drug Resistance Female Humans Male Middle Aged Ontario perioperative period Pilot Projects Platelet Aggregation - drug effects Platelet Aggregation Inhibitors - administration & dosage Platelet Aggregation Inhibitors - adverse effects Platelet Count Platelet Function Tests Thromboxane B2 - blood Time Factors Treatment Outcome
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!