Safety, potential efficacy, and pharmacokinetics of specific polyclonal immunoglobulin F(ab')2fragments against avian influenza A (H5N1) in healthy volunteers: a single-centre, randomised, double-blind, placebo-controlled, phase 1 study

Human infection with the avian influenza A H5N1 virus results in disease with a high fatality rate, against which antiviral treatments have limited efficacy. We aimed to investigate the safety, pharmacokinetics, and therapeutic potential of specific polyclonal immunoglobulin equine F(ab')2fragm...

Ausführliche Beschreibung

Bibliographische Detailangaben

Veröffentlicht in:	The Lancet infectious diseases 2015-03, Vol.15 (3), p.285
Hauptverfasser:	Bal, Céline, Herbreteau, Cécile H, Buchy, Philippe, Rith, Sareth, Zaid, Masliza, Kristanto, William, Han, Velda, Reynaud, Charlotte, Granjard, Patrick, Lépine, Bertrand, Durand, Caroline, Tambyah, Paul A
Format:	Artikel
Sprache:	eng
Schlagworte:	Body weight Drug dosages Fatalities Heart rate Hospitals Infections Infectious diseases Mortality Pharmacokinetics Safety
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!