Enteric Coating Can Lead to Reduced Antiplatelet Effect of Low‐Dose Acetylsalicylic Acid

Low‐dose acetylsalicylic acid (ASA) is widely used as antithrombotic prophylaxis. Enteric‐coated ASA has been developed to decrease the risk of gastrointestinal side effects. The consequences of enteric coating on pharmacokinetics and antiplatelet effect of ASA have not systematically been assessed....

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Veröffentlicht in:	Basic & clinical pharmacology & toxicology 2015-03, Vol.116 (3), p.212-215
Hauptverfasser:	Haastrup, Peter Fentz, Grønlykke, Thor, Jarbøl, Dorte Ejg
Format:	Artikel
Sprache:	eng
Schlagworte:	Aspirin - administration & dosage Aspirin - pharmacokinetics Aspirin - pharmacology Biological Availability Blood Platelets - drug effects Blood Platelets - metabolism Clinical Trials as Topic Humans Platelet Aggregation - drug effects Platelet Aggregation Inhibitors - administration & dosage Platelet Aggregation Inhibitors - pharmacokinetics Platelet Aggregation Inhibitors - pharmacology R&D Research & development Tablets, Enteric-Coated Thin film coatings
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