Environment Tobacco Smoke Exposure Affect Childhood Atopic Dermatitis Modified By TNF-[alpha] and TLR4 Polymorphisms

Environment Tobacco Smoke Exposure Affect Childhood Atopic Dermatitis Modified By TNF-[alpha] and TLR4 Polymorphisms

Conclusions Gene-environment interaction between prenatal/persistent ETS and TNF-[alpha]/TLR4 polymorphisms may play a role in AD development in school children. [...]reducing ETS exposure from prenatal period might be useful in preventing childhood AD, especially in susceptible population.

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Veröffentlicht in:Journal of allergy and clinical immunology 2015-02, Vol.135 (2), p.AB109
Hauptverfasser: Choi, Kil-Yong, Yang, Song-I, Lee, Eun, Jung, Young Ho, Yu, Ho-Sung, Hong, Kyung-Mo, Seo, Ju-Hee, Kwon, Ji-Won, Kim, Hyo-Bin, Kim, Byoung-Ju, Lee, So Yeon, Song, Young-Hwa, Kwon, Ho-Jang, Hong, Soo-Jong
Format: Artikel
Sprache:eng
Schlagworte:
Asthma
Children & youth
Health risk assessment
Tobacco smoke
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Zusammenfassung:Conclusions Gene-environment interaction between prenatal/persistent ETS and TNF-[alpha]/TLR4 polymorphisms may play a role in AD development in school children. [...]reducing ETS exposure from prenatal period might be useful in preventing childhood AD, especially in susceptible population.
ISSN:0091-6749
1097-6825
DOI:10.1016/j.jaci.2014.12.1292