Effects of Lettuce Glycoside B in Ameliorating Pulmonary Fibrosis Induced by Irradiation Exposure and its Anti-Oxidative Stress Mechanism

The present research assessed the effects of lettuce glycoside B (LGB), a compound separated and purified from Pterocypsela laciniata , on irradiation-induced pulmonary fibrosis and explored the mechanism involved. Animal model of irradiation exposure inducing pulmonary fibrosis was established by C...

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Veröffentlicht in:	Cell biochemistry and biophysics 2015-03, Vol.71 (2), p.971-976
Hauptverfasser:	Zhou, Yan, Gao, Yuan, Chen, Yingying, Zheng, Rui, Zhang, Wei, Tan, Mingqi
Format:	Artikel
Sprache:	eng
Schlagworte:	Animal models Animals Antioxidants Antioxidants - pharmacology Antioxidants - therapeutic use Biochemistry Biological and Medical Physics Biomedical and Life Sciences Biophysics Biotechnology Cell Biology Gamma Rays - adverse effects Glycosides - pharmacology Glycosides - therapeutic use Interleukin-6 - blood Irradiation Lactuca - chemistry Life Sciences Male Original Paper Oxidative Stress Pharmacology/Toxicology Plant Extracts - pharmacology Plant Extracts - therapeutic use Pulmonary Fibrosis - drug therapy Pulmonary Fibrosis - etiology Pulmonary Fibrosis - metabolism Rats Rats, Sprague-Dawley Superoxide Dismutase - blood Transforming Growth Factor beta1 - blood Tumor Necrosis Factor-alpha - blood
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