Pharmacokinetics for once-daily modified release formulation of tacrolimus hydrate in unrelated hematopoietic stem cell transplantation

A once-daily modified release formulation of oral tacrolimus (Tac QD) has been developed in response to the problem of nonadherence. However, there have been no data available about the efficacy of Tac QD conversion from intravenous Tac (Tac i.v.) in allogeneic hematopoietic stem cell transplantatio...

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Veröffentlicht in:	Annals of hematology 2015-03, Vol.94 (3), p.491-496
Hauptverfasser:	Yano, Shingo, Mori, Shinichiro, Saito, Takeshi, Yokoyama, Hiroki, Machishima, Tomohito, Shimada, Takaki, Yahagi, Yuichi, Sugiyama, Katsuki, Ogasawara, Yoji, Takahara, Shinobu, Kasama, Kinuyo, Katsube, Atsushi, Kamiyama, Yutaro, Suzuki, Kazuhito, Inui, Yumiko, Usui, Noriko, Aiba, Keisuke, Yamashita, Takuya
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Aged Delayed-Action Preparations Drug Administration Schedule Female Hematology Hematopoietic Stem Cell Transplantation - methods Humans Immunosuppressive Agents - administration & dosage Immunosuppressive Agents - pharmacokinetics Leukemia - metabolism Leukemia - therapy Lymphoma, Non-Hodgkin - metabolism Lymphoma, Non-Hodgkin - therapy Male Medicine Medicine & Public Health Middle Aged Myelodysplastic Syndromes - metabolism Myelodysplastic Syndromes - therapy Oncology Original Article Tacrolimus - administration & dosage Tacrolimus - pharmacokinetics Transplantation Conditioning - methods Transplantation, Homologous Unrelated Donors Young Adult
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