Composition and variation analysis of TCR [beta]-chain CDR3 repertoire in the thymus and spleen of MRL/lpr mouse at different ages

T cells play an important role in the onset and progression of systemic lupus erythematosus (SLE), and the biases in T cell receptor beta variable (TRBV) region families and complementarity determining region three (CDR3) composition in SLE patients and mouse models have been widely reported. Howeve...

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Veröffentlicht in:	Immunogenetics (New York) 2015-01, Vol.67 (1), p.25
Hauptverfasser:	Li, Zhou, Long, Ma, Chunmei, Liu, Bin, Shi, Jiang, Yu, Rui, Ma, Qingqing, Ma, Xinsheng, Yao
Format:	Artikel
Sprache:	eng
Schlagworte:	Apoptosis Blood Laboratory animals Lupus Lymphocytes Mutation Spleen T cell receptors Thymus gland
Online-Zugang:	Volltext
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