Adenosine activates brown adipose tissue and recruits beige adipocytes via A^sub 2A^ receptors

Brown adipose tissue (BAT) is specialized in energy expenditure, making it a potential target for anti-obesity therapies. Following exposure to cold, BAT is activated by the sympathetic nervous system with concomitant release of catecholamines and activation of β-adrenergic receptors. Because BAT th...

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Veröffentlicht in:	Nature (London) 2014-12, Vol.516 (7531), p.395
Hauptverfasser:	Gnad, Thorsten, Scheibler, Saskia, von Kügelgen, Ivar, Scheele, Camilla, Kilic, Ana, Glöde, Anja, Hoffmann, Linda S, Reverte-Salisa, Laia, Horn, Philipp, Mutlu, Samet, El-Tayeb, Ali, Kranz, Mathias, Deuther-Conrad, Winnie, Brust, Peter, Lidell, Martin E, Betz, Matthias J, Enerbäck, Sven, Schrader, Jürgen, Yegutkin, Gennady G, Müller, Christa E, Pfeifer, Alexander
Format:	Artikel
Sprache:	eng
Schlagworte:	Adipocytes Adipose tissue Body fat Cold NMR Nuclear magnetic resonance Obesity Physiology Rodents Thermogenesis Tissues
Online-Zugang:	Volltext
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