Hepatocyte growth factor/c-Met signaling is required for [beta]-cell regeneration

Hepatocyte growth factor (HGF) is a mitogen required for [beta]-cell replication during pregnancy. To determine whether HGF/c-Met signaling is required for [beta]-cell regeneration, we characterized mice with pancreatic deletion of the HGF receptor, c-Met (PancMet KO mice), in two models of reduced...

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Veröffentlicht in:	Diabetes (New York, N.Y.) N.Y.), 2014-01, Vol.63 (1), p.216
Hauptverfasser:	Alvarez-Perez, Juan Carlos, Ernst, Sara, Demirci, Cem, Casinelli, Gabriella P, Mellado-Gil, Jose Manuel D, Rausell-Palamos, Francisco, Vasavada, Rupangi C, Garcia-Ocana, Adolfo
Format:	Artikel
Sprache:	eng
Schlagworte:	Cell proliferation Cells Cellular signal transduction Correlation analysis Genetic aspects Growth factors Identification and classification Insulin Pregnancy Rodents
Online-Zugang:	Volltext
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