[beta]-Functionalization of Carboxylic Anhydrides with [beta]-Alkyl Substituents through Carbene Organocatalysis

The first NHC-catalyzed functionalization of carboxylic anhydrides is described. In this reaction, the [beta]carbon behaves as a nucleophilic carbon and undergoes asymmetric reactions with electrophiles. Anhydrides with challenging [beta]-alkyl substituents work effectively.

Bibliographische Detailangaben

Veröffentlicht in:	Angewandte Chemie 2014-12, Vol.126 (49), p.13724
Hauptverfasser:	Jin, Zhichao, Chen, Shaojin, Wang, Yuhuang, Zheng, Pengcheng, Yang, Song, Chi, Yonggui Robin
Format:	Artikel
Sprache:	ger
Schlagworte:	Chemistry
Online-Zugang:	Volltext
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