Molecular mechanisms of disease-related human [beta]-actin mutations p.R183W and p.E364K

Cytoplasmic [beta]-actin supports fundamental cellular processes in healthy and diseased cells including cell adhesion, migration, cytokinesis and maintenance of cell polarity. Mutations in ACTB, the gene encoding cytoplasmic [beta]-actin, lead to severe disorders with a broad range of symptoms. The...

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Veröffentlicht in:	The FEBS journal 2014-12, Vol.281 (23), p.5279
Hauptverfasser:	Hundt, Nikolas, Preller, Matthias, Swolski, Olga, Ang, Angella M, Mannherz, Hans G, Manstein, Dietmar J, Muller, Mirco
Format:	Artikel
Sprache:	eng
Schlagworte:	Cellular biology Disease Genotype & phenotype Molecular biology Mutation
Online-Zugang:	Volltext
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