A Naphthalimide-Based Fluorescence "Turn-On" Probe for the Detection of Pb2+ in Aqueous Solution and Living Cells

An easily available naphthalimide‐based fluorescent probe NPA for Pb2+ detection was successfully developed. NPA exhibited an obvious fluorescence turn‐on response toward Pb2+ in aqueous solution and in living cells. Moreover, a series of model compounds were rationally designed and synthesized in o...

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Veröffentlicht in:Chemistry, an Asian journal an Asian journal, 2014-12, Vol.9 (12), p.3397-3402
Hauptverfasser: Un, Hio-Ieng, Huang, Chang-Bo, Huang, Junhai, Huang, Chusen, Jia, Ti, Xu, Lin
Format: Artikel
Sprache:eng
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Zusammenfassung:An easily available naphthalimide‐based fluorescent probe NPA for Pb2+ detection was successfully developed. NPA exhibited an obvious fluorescence turn‐on response toward Pb2+ in aqueous solution and in living cells. Moreover, a series of model compounds were rationally designed and synthesized in order to explore the sensing mechanism and binding mode of NPA with Pb2+. See where things lead: A naphthalimide‐based fluorescence “turn‐on” probe NPA for the detection of Pb2+ in aqueous solution and living cells has been developed.
ISSN:1861-4728
1861-471X
DOI:10.1002/asia.201402946